Rui Lima PERSONAL DATA

 

 

Rui Lima NAME

Rui Alberto Madeira Macedo de Lima


Rui Lima ACADEMIC QUALIFICATIONS

Dipl.-Eng.(Minho Univ., Portugal), MSc-Eng.(Sheffield Univ., UK), PhD (Tohoku Univ., Japan).


Rui Lima PRESENT POSITION

Associate Professor at METRICS/DEM, University of Minho (UM), Portugal.

Research Fellow at CEFT/FEUP, University of Porto, Portugal.

External Collaborator at ESTiG, Polytechnic Institute of Braganca (IPB), Portugal.

Rui Lima Research IDs

Scopus ID: 18437397800

ORCID iD: 0000-0003-3428-637X

 
Rui Lima

Rui Lima RESEARCH FIELDS

Microfluidics, Nanofluidics, Biomicrofluidics, Microcirculation, Biofluid mechanics, Blood-on-chips.
Conventional and Confocal micro-PIV.
Energy and Environment.

 

Rui Lima

 

Rui Lima

 

Rui Lima

 

 

Rui Lima

Rui Lima PAPERS IN INTERNATIONAL JOURNALS AND BOOKS (SELECTED)

2018 Bento, D.; Rodrigues, R.O.; Faustino, V.; Pinho, D.; Fernandes, C.S.; Pereira, A.I.; Garcia, V.; Miranda, J.M.; Lima, R., Deformation of Red Blood Cells, Air Bubbles, and Droplets in Microfluidic Devices: Flow Visualizations and Measurements, Micromachines, 9, 151, 2018. https://www.mdpi.com/2072-666X/9/4/151

2018 Anes C. F., Pinho D., Munoz-Sanchez B. N., Vega E. J.; Lima R.; Shrinkage and colour in the production of micro-sized PDMS particles for microfluidic applications, Journal of Micromechanics and Microengineering, 28, 075002, 2018.

2017 Bento D., Sousa D., Yaginuma T., Garcia V., Lima R., Miranda JM, Microbubble moving in blood flow in microchannels: effect on the cell-free layer and cell local concentration, Biomedical Microdevices, 19 (1), 6, 2017.

2016 Rodrigues, R.O., Banobre-Lopez, M., Gallo, J., Tavares, P.B., Silva, A.M.T., Lima, R., Gomes, H.T., Hemocompatibility of Iron Oxide Nanoparticles synthetized for Theranostic Applications: a Novel Microfluidic Study, Journal of Nanoparticle Research, 18 (7), 1-17. 2016.

2016 Faustino V., SO Catarino S. O., Lima R., Minas G., Biomedical microfluidic devices by using low-cost fabrication techniques: A review, Journal of biomechanics, 49 (11), 2280-2292, 2016.

2016 Pinho D.; Rodrigues R. O., Faustino V., Yaginuma T., Exposto J., Lima R., Red blood cells radial dispersion in blood flowing through microchannels: the role of temperature, Journal of biomechanics, 49 (11), 2293-2298, 2016.

2016 Rodrigues R.O., Pinho D., Bento D., Lima R., Ribeiro J., Wall expansion assessment of an intracranial aneurysm model by a 3D Digital Image Correlation System, Measurement, 88, 262-270, 2016.

2016 Munoz-Sanchez B. N, Silva S. F., Pinho D., Vega E. J., and Lima R., 2016. Generation of micro-sized PDMS particles by a flow focusing technique for biomicrofluidics applications. Biomicrofluidics 10, 014122, 2016.

2016 J Calejo, D Pinho, FJ Galindo-Rosales, R Lima, L Campo-Deano, "Particulate Blood Analogues Reproducing the Erythrocytes Cell Free Layer in a Microfluidic Device Containing a Hyperbolic Contraction", Micromachines 7 (1), 4. http://www.mdpi.com/2072-666X/7/1/4/htm

2015 RO Rodrigues, D Pinho, V Faustino, R Lima, "A simple microfluidic device for the deformability assessment of blood cells in a continuous flow", Biomedical microdevices 17:108, 1-9.

2015 RO Rodrigues, R Lima, HT Gomes, AMT Silva, "Polymer microfluidic devices: an overview of fabrication methods", U. Porto Journal of Engineering 1 (1), 67-79. http://www.open-jim.org/index.php/upjeng/article/view/113/113

2015 E Pinto, V Faustino, RO Rodrigues, D Pinho, V Garcia, JM Miranda, R Lima, "A Rapid and Low-Cost Nonlithographic Method to Fabricate Biomedical Microdevices for Blood Flow Analysis", Micromachines 6 (1), 121-135. http://www.mdpi.com/2072-666X/6/1/121/htm

2014 V Faustino, D Pinho, T Yaginuma, RC Calhelha, ICFR Ferreira, R Lima, "Extensional flow-based microfluidic device: deformability assessment of red blood cells in contact with tumor cells", BioChip Journal 8 (1), 42-47. http://bibliotecadigital.ipb.pt/bitstream/10198/9678/1/BioChipMS_BICJ-D-13-00058_IPB.pdf

2014 B Taboada, FC Monteiro, R Lima, "Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model", Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, DOI:10.1080/21681163.2014.957868.

2013 D Pinho, T Yaginuma, R Lima, "A microfluidic device for partial cell separation and deformability assessment", BioChip Journal 7 (4), 367-374. https://bibliotecadigital.ipb.pt/bitstream/10198/9504/1/BioChip_Diana2013_IPB.pdf

2013 Yaginuma, T., M. S. N. Oliveira, Lima, R., Ishikawa, T., Yamaguchi T. " Human red blood cell behavior under homogeneous extensional flow in a hyperbolic-shaped microchannel", Biomicrofluidics, 7, 054110.

2013 Pinho, D., Gayubo, F., Pereira A. I., Lima, R. "A comparison between a manual and automatic method to characterize red blood cell trajectories." International Journal for Numerical Methods in Biomedical Engineering, 29(9), 977-987.

2013 Lima R., Ishikawa T., Imai Y., Yamaguchi T., "Confocal micro-PIV/PTV measurements of the blood flow in micro-channels", In: M.W.Collins & C.S.Konig (Eds), Nano and Micro Flow Systems for Bioanalysis, Springer, pp.131-151.

2012 Lima R., Joseyphus R. J., Ishikawa T., Imai Y., Yamaguchi T., "Micro-Flow Visualization of Magnetic Nanoparticles for Biomedical Applications." In Dias R, Martins AA, Lima R, Mata TM (Eds), Single and two-Phase Flows on Chemical and Biomedical Engineering,. Bentham Science Publishers: Netherlands, pp.513-547.

2012 Lima R., Ishikawa T, Imai Y, Yamaguchi T., "Blood flow behavior in microchannels: advances and future trends." In Dias R, Martins AA, Lima R, Mata TM (eds), Single and two-Phase Flows on Chemical and Biomedical Engineering, Bentham Science Publishers: Netherlands, pp.513-547. https://bibliotecadigital.ipb.pt/bitstream/10198/7409/3/eBookChapter20vIPB.pdf

2012 Garcia V., Dias R., Lima R., "In Vitro Blood Flow Behaviour in Microchannels with Simple and Complex Geometries", In: Ganesh R. Naik (ed.), Applied Biological Engineering: Principles and Practice, InTech, 17, pp.393-416. http://cdn.intechopen.com/pdfs-wm/33837.pdf

2011 Leble V., Lima R., Dias R. P., Fernandes C. S., Ishikawa T., Imai Y., Yamaguchi T. "Asymmetry of red blood cell motions in a microchannel with a diverging and converging bifurcation." Biomicrofluidics, 5, 044120.

2011 Lima, R., et al., "Microscale flow dynamics of red blood cells in microchannels: an experimental and numerical analysis", In: Tavares and Jorge (Eds), Computational Vision and Medical Image Processing: Recent Trends, Springer, Vol.19, 297-309.

2009 Lima, R., et al., "Measurement of individual red blood cell motions under high hematocrit conditions using a confocal micro-PTV system" Annals of Biomedical Engineering, 37, 1546-59.

2009 Lima, R., et al., "Axisymmetric polydimethysiloxane microchannels for in vitro hemodynamic studies" Biofabrication, 1, 3, 035005.

2009 Lima, R., et al., "Measurement of individual red blood cell motions under high hematocrit conditions using a confocal micro-PTV system" Annals of Biomedical Engineering, 37, 1546-59.

2009 Fujiwara, H., et al., "Red blood cell motions in a high hematocrit blood flowing through a stenosed micro-channel" Journal of Biomechanics, 42, 838-843.

2008 Lima, R., et al., "Radial dispersion of red blood cells in blood flowing through glass capillaries: role of heamatocrit and geometry" Journal ofBiomechanics, 41, 2188-2197.

2008 Lima, R., et al., "In vitro blood flow in a rectangular PDMS microchannel: experimental observations using a confocal micro-PIV system." Biomedical Microdevices,10(2),153-67.

2007 Lima, R.. et al., "Velocity fields of blood flow in microchannels using a confocal micro-PIV system." In: Future Medical Engineering based on Bio-nanotechnology Esashi, M., Ishi, K., Ohuchi, N., Osumi, N., Sato, M. and Yamaguchi, T. (eds), ICP.

2007 Lima, R.. et al. In vitro confocal micro-PIV measurements of blood flow in a square microchannel: the effect of the haematocrit on instantaneous velocity profiles. Journal of Biomechanics,40, 2752-2757.

2006 Lima, R.. et al., Confocal micro-PIV measurements of three dimensional profiles of cell suspension flow in a square microchannel. Meas. Sci. Tech.,17, 797-808.

2006 Tsubota, K. et al. A particle method for blood flow simulation: application to flowing red blood cells and platelets. Journal of the Earth Simulator,5, pp 2-7,.

2003 Lima, R.., Saloca, M., An effective thermal technology for the detoxification of the MSW fly ash. International Journal of Environmental Technology and Management. 3(2), 212-218.

2002 Lima, R.., Bachmann, R.., Pollutant emissions from modern incinerators. International Journal of Environment and Pollution, 18(4), 336-345.

 

 

Rui Lima

Rui Lima

Rui Lima

Rui Lima PAPERS IN INTERNATIONAL CONFERENCES (SELECTED)

2015 Raquel Lopes, Raquel O Rodrigues, Diana Pinho, Valdemar Garcia, Helmut Schutte, Rui Lima, Stefan Gassmann, "Low cost microfluidic device for partial cell separation: micromilling approach",Industrial Technology (ICIT), 2015 IEEE International Conference on, 3347-3350. https://bibliotecadigital.ipb.pt/bitstream/10198/12014/1/0712559.pdf

2014 Pinho, D., Rodrigues, R.O., Yaginuma, T. et al. "Motion of rigid particles flowing in a microfluidic device with a pronounced stenosis: Trajectories and deformation index", 11th World Congress on Computational Mechanics, Barcelona, Spain.

2013 V. Rodrigues, P. J. Rodrigues, A.I. Pereira, R. Lima, Automatic tracking of red blood cells in microchannels using OpenCV. AIP Conference Proceedings, Greece.

2013 F. C. Monteiro, B. Taboada, R. Lima, Visualization of red blood cells flowing through a PDMS microchannel with a microstenosis: an image analysis assessment, in Proceedings of ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing, Madeira, Portugal.

2012 D. Bento, P. Diana, A. I. Pereira, R. Lima, Cell-free layer (CFL) analysis in a glass capillary: Comparison between a manual and automatic method, in AIP Proceedings, Vol. 1479, Proceedings of the International Conference on Numerical Analysis and Applied Mathematics, pp. 786-789, Greece, September.

2012 V. Leble, C. Fernandes, R. Dias, R. Lima, T. Ishikawa, Y. Imai, T. Yamaguchi . Flow visualization of trace particles and red blood cells in a microchannel with a diverging and converging bifurcation. ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing, Olhao, Portugal, 12-14 October.

2012 T. Yaginuma, A.I. Pereira, P.J. Rodrigues, R. Lima, M.S.N. Oliveira, T. Ishikawa, T. Yamaguchi, Flow of red blood cells through a microfluidic extensional device: an image analysis assessment. ECCOMAS Thematic Conference on Computational Vision and Medical Image , Olhao, Portugal, 12-14 October.

2011 T. Yaginuma, M.S.N. Oliveira, R. Lima, T. Ishikawa, T. Yamaguchi. Red blood cell deformation in flows through a PDMS hyperbolic microchannel. Proceedings of TechConnect World 2011. Microtech Conference and Expo Boston, MA, USA, 13-16 June.

2011 D. Pinho, F. Gayubo, A.I. Pereira, R. Lima. A comparison between a manual and automatic method to characterize red blood cell trajectories. AIP Conference Proceedings, Halkidiki, Greece, 19-25 September.

2011 C.S. Fernandes, R. Lima, R.P. Dias 2011. Numerical Prediction of Velocity, Pressure and Shear Rate Distributions in Stenosed Channels. Proceedings of the 10th International Conference on Computational and Mathematical Methods in Science and Engineering, CMMSE2011, Beenidorm, Spain, 26-30 June.

2011R. Lima 2011. Micro-flow visualization of blood cells motions under High hematocrits conditions. Workshop on Microscale Modeling in Biomechanics and Mechanobiology. Ericeira, Portugal.

2011 R. Lima, M. S. N. Oliveira, T. Yaginuma, T. Ishikawa, Y. Imai, T. Yamaguchi. Development of a Microfluidic Device for Partial Cell Separation. Japan-Portugal Nano-BME Symposium, Porto/Braganca, Portugal, 3-6 June.

2011 F. T. Pinho, R. Lima, M. A. Alves, M. S. N. Oliveira. Transport Phenomena Research Center (CEFT): Research on Complex Flows of Complex Fluids. Japan-Portugal Nano-BME Symposium, Porto/Braganca, Portugal, 3-6 June.

2011 D. Pinho, F. Gayubo, A. I. Pereira, R. Lima. Tracking Erythrocytes in a 100 m Glass Capillary. Japan-Portugal Nano-BME Symposium, Porto/Braganca, Portugal, 3-6 June.

2011 V Leble, R. Dias, R. Lima, C. Fernandes, T. Ishikawa, Y. Imai, T. Yamaguchi 2011. Motions of Trace Particles and Red Blood Cells in a PDMS Microchannel with a Converging Bifurcation. Japan-Portugal Nano-BME Symposium, Porto/Braganca, Portugal, 3-6 June.

2010 Lima, R., et al., Blood-on-chips: flow through complex geometries, 6th World Congress of Biomechanics, Singapore.

2010 Lima, R., Flow Behaviour of Labeled Red Blood Cells in Microchannels : a confocal micro-PTV assessment, 6th World Congress of Biomechanics, Singapore.

2010 Lima, R., et al., Measuring the Cell-Free Layer in circular Microchannels, 6th World Congress of Biomechanics, Singapore.

2010 Garcia, V., et al., Flow of physiological fluids in microchannels: the sedimentation effect, 6th World Congress of Biomechanics, Singapore.

2010 Pinho, D., et al., Red Blood Cell dispersion in 100 m glass capillaries: the temperature effect , 6th World Congress of Biomechanics, Singapore.

2010 Queijo, L., Lima, R., PDMS Anatomical Realistic Models for Hemodynamic Studies Using Rapid Prototyping Technology, 6th World Congress of Biomechanics, Singapore.

2010 Lima, R., et al., Confocal micro-flow visualization of blood cells, V European Conference on Computational Fluid Dynamics, ECCOMAS CFD 2010, Lisbon, Portugal.

2010 Freitas, V., Rapid prototyping of 3D anatomical models to hemodynamic studies, International Conference on Biomedical Electronics and Devices. Valencia.

2009 Diana, P., et al., Motion of Red Blood Cells in a Glass Microchannel: A Global Optimization Approach, International Conference on Numerical Analysis and Applied Mathematics, Greece, 1168, 1362-1365.

2009 Lima, R., et al., Motions of particles and red blood cells in a bifurcation: comparison between experiments and numerical simulations, ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing, Porto, Portugal.

2009 Lima, R., et al., Determination of the cell-free layer in circular PDMS microchannels, ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing, Porto, Portugal.

2009 Ishikawa, T., et al., Individual motions of red blood cells in high-hematocrit blood flowing in a microchannel with complex geometries, Proceedings of the ASME 2009 (SBC2009), USA.

2009 Ishikawa, T., et al., Motion of individual red blood cells in a concentrated suspension flowing through micro-channels,In: Proceedings of APBio 2009, New Zealand.

2008 Ishikawa, T.,, et al., Mixing of Red Blood Cells in a Micro-channel Flow under High Hematocrit conditions, In: Proceedings of Bioengineering 08, Imperial College London, London, UK.

2008 Lima, R., et al., Confocal micro-PTV Measurements of Blood Flow in a Circular PDMS Microchannel, In: Proceedings of Bioengineering 08, Imperial College London, London, UK.

2008 Fujiwara, H., et al., Motion of Red Blood Cells and Cell Free Layer Distribution in a Stenosed Microchannel, In: Proceedings of 16th Congress of the European Society of Biomechanics, Lucerne, Switzerland.

2008 Lima, R., et al., The role of the hematocrit on the radial dispersion of red blood cells in glass capillaries, In: Proceedings of 16th Congress of the European Society of Biomechanics, Lucerne, Switzerland.

2008 Lima, R., et al., Determination of Blood Cells Motions and Interactions by a Confocal Micro-PIV System, In: Proceedings of 16th Congress of the European Society of Biomechanics, Lucerne, Switzerland.

2008 Lima, R., et al., Dispersion of Red Blood Cells in microchannels : A confocal micro-PTV assessment, In: Proceedings of the 20th Bioengineering Conference, 2007 Annual Meeting of BE/JSME, Tokyo, Japan.

2007 Lima, R., et al., Microscale flow dynamics of red blood cells in a circular microchannel, ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing, Porto, Portugal.

2007 Fujiwara H., et al., Tracking of Red Blood Cells in Microchannel with Stenosis by Confocal Micro PTV System, AFI/TFI,Sendai, Japan.

2007 Lima, R., et al., Measurement of multi-red blood cells interactions in blood flow by confocal micro-PTV, Third Asian Pacific Conference on Biomechanics, Tokyo, Japan.

2007 Fujiwara, H., et al., Observation of blood flow in amicrochannel with stenosis by confocal micro-PIV, Third Asian Pacific Conference on Biomechanics, Tokyo, Japan.

2007 Lima, R., et al., Tracking Red blood cells in a circular PDMS Microchannel using a Confocal micro-PIV System, In: International Symposium of Future Medical Engineering based on Bio-nanotechnology, Sendai, Japan.

2007 Lima, R., et al., Measurement of erythrocyte motions in microchannels by using a confocal micro-PTV, In: ASME 2007 Summer Bioengineering Conference, Colorado, USA.

2007 Lima, R., et al., Blood cell motions and interactions in microchannels, Journal of the Visualization Society of Japan 27, Suppl. 1, pp.141-142.

2006 Lima, R., et al., Confocal micro-PIV measurements of blood flow in microchannels, 5th World Congress of Biomechanics, Munich, Germany (Journal of Biomechanics 39, Suppl. 1, S332).

2006 Lima, R., et al., Velocity measurements of blood flow in a rectangular PDMS microchannel assessed by confocal micro-PIV system. In: Proceedings of the World Congress on Medical Physics and Biomedical Engineering, Seoul, pp. 278-281.

2005Lima, R., et al., Analysis of velocity profiles of blood flow in microchannels using confocal micro-PIV and particle method, In: Proceedings of the II International Conference on Computational Bioengineering, IST, Portugal.

2005 Lima, R., et al., Confocal micro-PIV velocity measurements of physiological fluids in a Rectangular microchannel, In: Proceedings (CD ROM) of the 3rd IASTED International Conference on Biomechanics - BioMech 2005,Spain.

2005 Lima, R., et al., Velocity measurements of physiological flows in microchannels using a confocal micro-PIV System, In: Proceedings of the 16th JSME Conference on Frontiers in Bioengineering, Kusatsu Japan.

 

Rui Lima

Rui Lima FUNDED RESEARCH PROJECTS (SELECTED)

2018 NFsCoolingSystem: An advanced microCooling System based on innovative NanoFluids and acoustic streaming, project approved by FCT (Portuguese Science and Technology Foundation), (Project Leader).

2018 RTChip4Theranostics: Real Time Liver-on-a-chip platform with integrated micro(bio)sensors for preclinical validation of graphene-based magnetic nanocarriers towards cancer theranostics, project approved by FCT (Portuguese Science and Technology Foundation), (Project Member).

2017 BiomimeticFluids: Development of biomimetic designer fluids for biomedical applications, project approved by FCT (Portuguese Science and Technology Foundation), (Project Member).

2017 NEXT-SEA - Next generation monitoring of coastal ecosystems in a scenario of global change, project approved by NORTE-01-0145-FEDER-000032, (Project Member).

2014 MicroBloodSystems: Blood rheology and blood cell migration in microfluidic systems, project approved by FCT, (Project Member).

2012PTDC/SAU-ENB/116929/2010: "BIOMIMETIC - A biomimetic microdevice for the diagnosis of erythrocytes diseases based on their deformability", Portuguese Science and Technology Foundation, FCT (Project Leader).

2009 PTDC/SAU-BEB/105650/2008: "CSD-Chip - Development of an integrated biomedical microdevice for blood cell separation and deformation", Portuguese Science and Technology Foundation, FCT (Project Leader).
http://csdchip.ipb.pt/index.html

2009 PTDC/SAU-BEB/108728/2008: "Hemo-Networks - Experimental and computational investigations of the factors influencing blood flow in microvascular networks", Portuguese Science and Technology Foundation, FCT (Project Member).

2009 PTDC/SAU-BEB/105650/2008: "ANEURYSM - Hemodynamic Study in Cerebral Aneurysms", Portuguese Science and Technology Foundation, FCT (Project Member).

 

Rui Lima

Rui Lima

Rui Lima POSTERS

Rui Lima Confocal micro-PIV measurements of blood cells suspension flow in a square microchannel
Rui Lima Red blood cells interactions in blood flow

Rui Lima Web SITES

METRICS, Mechanical Engineering and Resource Sustainability Center, MINHO UNIV., PORTUGAL.

http://www.metrics.pt/

Minho University

https://www.eng.uminho.pt/en/Pages/default.aspx

ResearchGate (Rui A. Lima)

https://www.researchgate.net/profile/Rui_Lima9

CEFT, Transport Phenomena Research Center, FEUP, PORTO UNIV., PORTUGAL.
http://paginas.fe.up.pt/~ceft/Welcome.html

ESTiG, IPB, PORTUGAL.
http://www.estig.ipb.pt/

PFSL, TOHOKU UNIV., JAPAN.
http://www.pfsl.mech.tohoku.ac.jp/index-en.html

 

Rui Lima Blood flow videos

Research items: Data

https://www.researchgate.net/profile/Rui_Lima9/publications


 

Rui Lima MAIL ADDRESS

DEM, MINHO UNIV., PORTUGAL
rl@dem.uminho.pt

ESTiG, IPB, PORTUGAL.
ruimec@ipb.pt

PFSL, TOHOKU UNIV., JAPAN.
rui@pfsl.mech.tohoku.ac.jp